Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in ...

Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in ...

A Collage of Defense We mainly curse mucus as we are blowing it from our noses or coughing it up from our lungs because of some allergy or ailment. However, mucus plays a key role in defending our ...

Gut support cells communicate with surprising precision – like brain neurons – using tiny extensions to send instructions to the stem cells responsible for maintaining and healing the intestine. The ...

This interplay between goblet cells and the gut microbiome is essential to sustaining both a strong immune defense and tolerance.” Dr. Fernanda Raya Tonetti, University of California ...

This effect was also recapitulated in vitro. TLR4 suppression is sufficient to convert the IEC-6 small intestinal enterocytes to goblet-like mucin-producing cells.

Gastric cardia intestinal metaplasia (CIM), denoted by goblet cells is common. The frequency of persistent CIM is unknown. 85 patients with CIM and follow-up endoscopies were prospectively ...

Goblet cells play a critical role in the rapid acquisition of allergens. In this case, they acted as gatekeepers, allowing swift access for allergens carried by pollen shells.

In the study, these specific goblet cells seemed to be repelled by the mucosa earlier than normal in patients with ulcerative colitis. Accordingly, the cells became fewer.

Defects in a specific cell type may cause ulcerative colitis Date: April 19, 2021 Source: University of Gothenburg Summary: There are many variants of 'goblet cells' in the intestines and they ...

BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states. Cell Reports, 2022; 38 (9): 110438 DOI: 10.1016/j.celrep.2022.110438 ...