This metabolic reprogramming provides the energy needed for tumor growth and is a key area for developing new cancer treatments. Researchers use the Agilent Seahorse XF platform to measure glycolysis ...

Cancer cells are highly dependent on metabolic pathways to generate energy for diverse oncogenic processes. Investigating how cancer cells reprogram their metabolism to adapt and survive can reveal ...

This led to a decrease in PDHA1 S293 phosphorylation and an increase in PDH enzyme activity, promoting oxidative phosphorylation and reducing glycolysis.

Villaronga-Luque and Savill observed that specifically, the balance between two different processes that produce energy—glycolysis and oxidative phosphorylation—affects the variability of the stem ...

When activated, these cells undergo metabolic reprogramming, thus triggering aerobic glycolysis and oxidative phosphorylation (OXPHOS) pathways for rapid cellular growth and proliferation.

News Release 11-Feb-2025 PAK5-mediated PKM2 phosphorylation is critical for anaerobic glycolysis in endometriosis Peer-Reviewed Publication Higher Education Press image: Fig 1 view more ...