Pathway-focused metabolite ratio-based analysis of 49 tumor and 8 normal epithelial cell lines grown in their respective ...

Glycolysis is a term used to describe the metabolic pathway involving the degradation of glucose into pyruvate and energy used to form adenosine triphosphate (ATP) and reduced nicotinamide adenine ...

The researchers found activating an enzyme called pyruvate kinase helps the pancreas’ beta ... Scientists have long understood that this increase in glucose metabolism is what turns on insulin ...

Also called the Embden-Meyerhof-Parnas pathway, glycolysis involves a glucose molecule being split ... two molecules each of ATP and NADH. How the pyruvate is then processed depends on whether ...

Little is known about the features of glucose metabolism in cells undergoing ... was used daily at 100 μM, sodium pyruvate (11360039, Life Technologies) was used at 5 mM daily, and NAcGluc ...

Enzyme kinetic data from the BRENDA database were mapped onto the genome-scale metabolic model of Saccharomyces cerevisiae to ...

Rapid and extensive Schwann cell death under high-glucose pyruvate-depleted conditions ... escalation of the polyol and other collateral glycolysis pathways, 4) impaired hexokinase (HK) activity ...

Researchers at the University at Buffalo, led by Dr. Mulchand Patel and also at Lawson Health Research Institute and Western Ontario, London, Canada, led by Dr. David Hill, collaboratively ...

Pyruvate is taken into cellular structures ... SIRT6's control of critical glucose-metabolic pathways could signify a contribution to lifespan regulation. Elevated glycolysis also is commonly ...

A research team has unveiled an adrenal independent pathway, the hypothalamus-sympathetic-liver (HSL) axis, to mediate stress-induced glucose release. Their study is published in Nature ...