Our natural glucocorticoid levels increase with age, and bone, at least when we are young, has more glucocorticoid receptors than mineralocorticoid receptors.

For older bone, she thinks mineralocorticoid receptors may be a better target. We thought that knocking out the glucocorticoid receptor would make things better, but it made them worse.

Our natural glucocorticoid levels increase with age, and bone, at least when we are young, has more glucocorticoid receptors than mineralocorticoid receptors. Glucocorticoids can actually coax stem ...

Article Open access Published: 01 September 2016 Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity Stefanie Schöne, Marcel Jurk, Mahdi Bagherpoor ...

In multivariable analysis using clinical judgment, older age (OR = 0.92; 95% CI, 0.86-0.99) and higher clinical activity score before glucocorticoid therapy (OR = 0.53; 95% CI, 0.31-0.9) were tied ...

Adrenal gland activity changes under severe stress causing abnormal release of glucocorticoid stress Date: July 17, 2017 Source: University of Bristol Summary: To respond to stress optimally, the ...

Glucocorticoid treatments contribute to organ damage accrual in patients with systemic lupus erythematosus, independent of clinical or serological disease activity, according to data published in ...

Glucocorticoid use was found to contribute to damage accrual in people with systemic lupus erythematosus independently of the presence of clinical signs or serological disease activity. In a cohort of ...

For older bone, she thinks mineralocorticoid receptors may be a better target. “We thought that knocking out the glucocorticoid receptor would make things better, but it made them worse,” ...

Our natural glucocorticoid levels increase with age, and bone, at least when we are young, has more glucocorticoid receptors than mineralocorticoid receptors.