Why can you possess traits neither of your parents have? The relationship of genotype to phenotype is rarely as simple as the dominant and recessive patterns described by Mendel. As opposed to ...

Phenotypic screening has re-emerged as a powerful strategy for identifying drugs based on their observable effects. Discover ...

In general, when we know that the genotype is present but the phenotype is not observable, the trait shows incomplete penetrance. Basically, anything that shows less than 100% penetrance is an ...

Lissencephaly and subcortical band heterotopia are closely related cortical malformations and are true disorders of neuronal migration. The genetic basis of approximately 70% of classic ...

John Brandsema, MD, a pediatric neurologist at Children’s Hospital of Philadelphia, speaks with Healio about the current understanding of the genetic factors behind muscular dystrophy.