Another protein, CTCF, attaches to locations of super-enhancer DNA and pairs them up with genes that they will later turn on during sperm development. This sets up a new structure that cements the ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Research shows UV radiation modifies 3D genome structure, affecting DNA damage response and gene activity, offering insights ...

But James Watson and Francis Crick's claim was a valid one, for they had in fact discovered the structure of DNA, the chemical that encodes instructions for building and replicating almost all ...

This non-coding DNA, sometimes referred to as "junk DNA," has various functions, such as regulating gene expression, maintaining chromosome structure, and playing a role in evolution. The size of an ...

Researchers analyze various aspects of gene regulation, among which are the three-dimensional structure of the genome and DNA methylation, which differ for different cell types and play significant ...

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process ...

Get Instant Summarized Text (Gist) The 3D structure of the genome plays a crucial role in sperm development by organizing DNA into a configuration that coordinates gene activity. This organization ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers ...