A large language model can design and troubleshoot CRISPR protocols from scratch, allowing first-time researchers to achieve ...

The preprint, published on bioRxiv on September 1, shows a much lower efficiency rate for the technique compared to the original report. The results of the new study indicate the limitations of the ...

Data published online in the journal Cytotherapy demonstrate that CRISPR-mediated tissue factor gene knockout (TFKO) in allogeneic stromal cells (ASCs) leads to significantly lower tissue factor ...

Traditional gene knockout methods, including CRISPR-Cas9, typically result in complete loss of function, making it difficult to investigate these vital genetic components.

Researchers can determine regulatory gene expression using the relatively accurate gene knockout method, where if a gene A is eliminated, a gene B -- that A had regulated -- is exposed.

Scientists have gene-edited a cane toad egg to prevent a hatchling growing past the tadpole stage. The gene knockout technique could be scaled up and potentially used to manage the invasive species.

More than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the brain lead to a host of altered behaviors, including issues with language, ...

Removing the PKCI/HINT1 gene from mice has an anti-depressant-like and anxiolytic-like effect. Researchers writing in the open access journal BMC Neuroscience applied a battery of behavioral tests to ...