A stark 82% of assessed patients with hereditary transthyretin (ATTRv) amyloidosis exhibited at least 1 gastrointestinal symptom, warranting the need for gastroenterologists in multidisciplinary ...

1. Cappello M, Barbara G, Bellini M, et al. Identification and management of gastrointestinal manifestations of hereditary transthyretin amyloidosis: Recommendations from an Italian group of experts.

PARAMYLOIDOSIS (or primary amyloidosis)1 is a rare condition, only about 70 cases having been reported in the literature. Paramyloid deposition is widespread in the body, and as a result its clinic ...

Of these 943 participants, 30.2% (n=285) were classified as having a high combined weighted symptom score (CWSS), which is based on the gastroparesis composite symptom index and GI symptom rating ...

Systemic amyloidosis is characterized by the extracellular deposition of protein in an abnormal and insoluble form. Involvement of the gastrointestinal tract is very common but is often subclinical.

Okuda Y and Takasugi K (2006) Successful use of a humanized anti-interleukin-6 receptor antibody, tocilizumab, to treat amyloid A amyloidosis complicating juvenile idiopathic arthritis. Arthritis ...

HELIOS-B is a global, Phase 3, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of vutrisiran in patients with ATTR amyloidosis with cardiomyopathy, which ...

Older patients with ATTR amyloidosis are at increased risk for developing severe COVID-19, requiring more careful social distancing, use of protective masks, and frequent hand washing Many older ...

The American College of Cardiology (ACC) has issued an expert consensus decision pathway highlighting the importance of recognizing and diagnosing cardiac amyloidosis early to allow the most ...