The new drug has already passed Phase 1 safety trials in humans, making it a "strong candidate" for future PTSD treatments.

Researchers discovered that PTSD may be driven by excess GABA from astrocytes, not neurons. This chemical imbalance disrupts ...

An experimental drug reverses PTSD-like symptoms in mice. The corresponding study was published in Signal Transduction and ...

Excessive levels of GABA released by astrocytes impair the brain's ability to extinguish fear responses in PTSD, but a newly ...

Serotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulation. J Neurosci. 2007 Jun 27;27 (26):6956-64. doi: 10.1523/JNEUROSCI.2584-06.2007.

Patients with post-traumatic stress disorder (PTSD) often struggle to forget traumatic memories, even long after the danger ...

Xu said. Serotonin is primarily synthesized by neurons in the dorsal Raphe nucleus (DRN) in the midbrain. Serotonin neurons in the DRN project to numerous brain regions, including the arcuate of the ...

Interestingly, serotonin regulates the expression of astrocyte genes involved in the production of the neurotransmitter GABA, which then feeds back to neurons regulating the neural circuit ...

If you’ve heard of two of the brain’s chemical neurotransmitters, it’s probably dopamine and serotonin. Never mind that glutamate and GABA do most of the work — it’s the thrill of dopamine as the ...