The new drug has already passed Phase 1 safety trials in humans, making it a "strong candidate" for future PTSD treatments.

What's more, the "go" neurotransmitter glutamate was found to be more actively signaling to GABAergic neurons – a dysregulated behavior that is also seen in dementia-related cognitive decline.

"We found that suppression of GABAergic neurons causes perseverance in a current or familiar goal; activation of glutamatergic neurons drives exploration of alternative options; and suppression of ...

Xiaojing Tang et al. at Chongqing Institute for Brain and Intelligence recently published a study in Science Bulletin titled “Parvalbumin Interneurons Are Essential for Tonotopy Strength in the ...

Conversely, in HW conditions, reduced activity of MPOA GABAergic neurons allows increased activity of PVNAVP neurons, likely involving AVP neurons, which is associated with depressive-like behaviors.

Multi-electrode arrays (MEAs) have revolutionized functional characterization of neurons and neural networks, offering researchers unprecedented insights into cellular activity and network dynamics.