"It really nicely revealed all the sequence and dependence of very well known biochemical proteins in the focal adhesions, and they act as a seed for the oldest mechanosensitive protein recruitment ...

For the study, the researchers first looked for mRNAs at the feet, which are also known as focal adhesions. Previous research had identified a handful of mRNAs that localized around focal adhesions.

Researchers are testing a new combination drug therapy that could both treat and prevent melanoma metastasis, or spreading ...

Maher, P. A. et al. Phosphotyrosine-containing proteins are concentrated in focal adhesions and intercellular junctions in normal cells. Proceedings of the National Academy of Sciences 82 ...

On binding to ECM molecules, integrins are thought to undergo a conformational change, which allows the intracellular domain of their β-subunit to interact with focal-adhesion proteins ...

Holmen and her team first examined what causes melanoma cells to spread to the brain and identified focal adhesion kinase (FAK) as a potential target for new therapies. FAK is an enzyme that regulates ...

A group of researchers from Arizona State University and University of Arizona have published their work on a new treatment ...

Holmen and her team first examined what causes melanoma cells to spread to the brain and identified focal adhesion kinase ...