A hemodialysis session lasting for 4–8 hours removed 40–65% of the administered metronidazole dose. Consider supplementing metronidazole dose after hemodialysis if metronidazole cannot be ...

Severe hepatic impairment (Child-Pugh C): reduce metronidazole dose by 50%. No dose adjustment needed for mild to moderate hepatic impairment, but monitor for metronidazole associated adverse events.