The fibrous proteins and ground substance produced by fibroblasts are what constitute the extracellular matrix (ECM), which makes up the bulk of connective tissue. The ECM has many roles within ...

Lennart Franzén, Claes Dahlquist, The Effect of Transforming Growth Factor-β on Fibroblast Cell Proliferation in Intact Connective Tissue in vitro, In Vitro Cellular & Developmental Biology. Animal, ...

Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of diseases. For a long time, these specialized connective tissue cells were ...

High glucose levels could impair ferroelectricity in body's connective tissues Date: April 15, 2013 Source: University of Washington Summary: New research suggests that more sugar in the body ...

A surprising level of activity discovered in “sleepy” cells throughout the human body could be a key to good health. Fibroblasts, which are found in connective tissue such as ligaments and tendons, ...

Umea University. "New cells in connective tissue open up strategy against pancreatic cancer." ScienceDaily. ScienceDaily, 23 April 2025. <www.sciencedaily.com / releases / 2025 / 04 / 250423112151 ...

More information: Katarzyna M. Sitnik et al, Fibroblasts are a site of murine cytomegalovirus lytic replication and Stat1-dependent latent persistence in vivo, Nature Communications (2023).

Dear B.M.: All three of the conditions you mention are related to excess growth of connective tissue. In the hand, Dupuytren’s contracture is caused by excess growth of a connective cell (called ...

University researchers have developed a new connective tissue model to study disorders like fibrosis, a type of scarring that occurs when damage to the body causes normal tissue to be replaced by hard ...

Fibroblasts are the main connective tissue cells present in the body. As well as being present as fibroblasts, these cells exist in an alternative state, as fibrocytes.