The fibroblasts were directly converted into iPULs (induced pulmonary epithelial-like cells)—functionally akin to native AT2 ...

Fibroblasts are the main connective tissue cells present in the body. As well as being present as fibroblasts, these cells exist in an alternative state, as fibrocytes.

During fibrosis, fibroblasts — connective tissue cells that synthesize the extracellular matrix — “become somehow dysregulated, either by injury or by mutation,” he added. “These fibroblast cells ...

Fibroblasts are also the culprits in problems caused by implants -- if the implant is too smooth, it never becomes properly incorporated into the connective tissue.

Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of diseases. For a long time, these specialised connective tissue cells were ...

One fascia progenitor, two fibroblast gates Wound healing is a conserved process that requires tight spatiotemporal tuning of consecutive phases. In the inflammatory phase, local signals trigger ...

Researchers have now developed an immunotherapy that specifically targets the cause -- activated fibroblasts -- while leaving normal connective tissue cells unharmed.

By seeing which genes are active in 768 individual connective tissue cells from a mouse model of breast cancer, we were able to identify three different subgroups of fibroblasts which differ in ...

The fibrous proteins and ground substance produced by fibroblasts are what constitute the extracellular matrix (ECM), which makes up the bulk of connective tissue. The ECM has many roles within ...