Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of diseases. For a long time, these specialised connective tissue cells were ...

Effects of embryonic origin, tissue cues and pathological signals on fibroblast diversity in humans. Nature Cell Biology , 2025; 27 (5): 720 DOI: 10.1038/s41556-025-01638-5 Cite This Page : ...

Collagen is the most abundant protein in the human body that provides structural support to connective tissues, including tendons, ligaments, cartilage, muscles, skin, and bones. ... There are no less ...

Background: Matrix metalloproteinases (MMPs) have a pivotal role in the destruction of cartilage in rheumatoid arthritis (RA), which is mediated by the fibroblast-like synoviocytes (FLS). Objective: ...

In order to discriminate inflammatory and fibroblast cells, a set of mathematical features viz., area, perimeter, eccentricity, compactness, Zernike moments and Fourier descriptors are extracted ...

Fibroblasts are easier to obtain than stem cells, since excess tissues from surgeries can be used as a source of connective tissue cells, according to FibroBiologics. Further, fibroblasts’ isolation ...

Your Good Health: Excess connective tissue cause of Peyronie's disease. Many men do not speak to their physician about the condition, which causes pain and deformity of the penis.

Background Connective tissue disease (CTD) is a group of autoimmune diseases characterized by the damage of connective tissue components in various parts of the body, which involved multiple organs ...