"Uncovering the role of Y chromosome genes in male fertility in mice." ScienceDaily. ScienceDaily, 23 January 2025. <www.sciencedaily.com / releases / 2025 / 01 / 250123163201.htm>.

When it comes to fertility, there’s even some published data showing that rapamycin can slow the diminishment of the ovarian reserve of—again—mice in labs.

If these genes were removed, the mice couldn’t produce young, due to the absence or reduced number of sperm, failure to produce a reservoir of sperm stem cells, or abnormal sperm shape or movement.

The study could serve as proof-of-concept for future fertility treatments aimed at reversing aging in human egg cells — but much more research is needed to translate these findings to people.

Generation of mice with deletion of a genomic locus harboring four reproductive tract–specific RNase A family genes. Credit: Journal of Biological Chemistry (2024). DOI: 10.1016/j.jbc.2024.107933 ...

TLE6, a major protein involved in early embryonic development, is known to affect female fertility. In a recent study, researchers unraveled its role in male fertility using a novel Tle6-deficient ...

The researchers noticed that male mice whose TAF4b gene was manipulated were only fertile for a month or two, whereas mice with intact TAF4b remained fertile for several years. “Cells that are ...

NEW YORK — Zika virus ravages the testes of male mice, sharply reducing sperm counts and fertility, says a study that raises a new spectre about its threat to people.

To study this, Diamond and colleagues injected male mice with Zika. After a week, the researchers recovered infectious virus from the testes and sperm, and they found evidence of viral genes in ...

After nine months in space, mouse sperm has yielded healthy mice. That's the word from Japanese scientists whose results were published Monday. The freeze-dried sperm samples were launched in 2013 ...