Cutting calories doesn’t just slim you down—it also reduces cysteine, an amino acid that flips fat cells from storage mode to ...

High-fat diets and obesity reshape astrocytes—star-shaped brain cells in the striatum that help regulate pleasure from eating ...

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide. This prevalent ...

These second- generation mice lack myostatin and also have a genetic change that causes obesity. One line of fat mice, officially named "obese," eat excessively because they lack the hormone leptin.

Obesity elevates the risk of at least 13 major cancers, including those of the breast, colon and liver. It also impairs immune responses that target tumors and are stimulated by cancer immunotherapies ...

Ozempic can cause loss of body weight that isn’t fat, raising concerns that the drug lowers muscle mass and strength. New ...

They are also developing additional mice models, where Nox1 and galectin-3 are removed from already genetically fat mice, to further explore their role in vascular dysfunction.

It's well established that obesity significantly increases your risk of many types of cancer, but a decade-long study has ...

After a month of treatment designed to increase TSLP levels the mice showed significant improvements to blood glucose. But surprisingly, the animals also dropped huge volumes of visceral fat.

High-fat diets have previously been shown to alter the gut microbiome of mice, and of their immediate offspring. In a 2016 study, some of the authors of the current paper showed that male pups born to ...

Ye and his colleagues then asked what the function of these sensory nerves is. They first sought a way to target and remove them, engineering a viral vector to specifically kill sensory cells ...

Mice experimentally treated so that Clostridia were the only bacteria living in their gut were leaner with less fat than mice that had no microbiome at all. They also had lower levels of a gene, CD36, ...