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Your patient with gout is undergoing evaluation prior to initiation of urate-lowering therapy (ULT). According to the American College of Rheumatology (ACR) guidelines, anti-inflammatory prophylaxis ...

High uric acid is a health concern. It links to gout, kidney issues, and heart problems. Obesity and diabetes worsen it. The ...

The European Alliance of Associations for Rheumatology - recommends that serum urate should be maintained at <6 mg/dL (360 µmol/L) and <5 mg/dL (300 µmol/L) in those with severe gout.

Severe gout can cause uric-acid nephrolithiasis and medullary deposition of MSU, leading to interstitial nephropathy (as diagnosed in our patient).