The lab's focus is on developing tools that allow scientists to build upon the intrinsic properties of cells to assemble 3D tissues and synthesize their own extracellular matrix, Morgan explained.

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“In this paper, we develop a 3D connective tissue model that enables us to directly quantify how exposing cells in a 3D environment to different nutrients, growth factors or drug treatments results in ...

0:00 / 0:00 Highlights: Ovarian cancer cells are drawn to the extracellular matrix of aged tissues, influencing their spread Senescence induced by chemotherapy may worsen outcomes in ovarian cancer ...

Fibroblasts are found in the connective tissue of our organs, where they ensure that the extracellular matrix is continuously renewed and remains healthy. If an injury occurs or tissue growth is ...

The findings suggest that connective tissue, and extracellular matrix proteins like lumican, operate outside of cells normally, but as disease or damage break down ECM, get sucked into and ...

The findings suggest that connective tissue, and extracellular matrix proteins like lumican, operate outside of cells normally, but as disease or damage break down ECM, get sucked into and ...

More information: Hyeonji Kim et al, Extracellular matrix-based sticky sealants for scar-free corneal tissue reconstruction, Biomaterials (2022). DOI: 10.1016/j.biomaterials.2022.121941 ...