“In this paper, we develop a 3D connective tissue model that enables us to directly quantify how exposing cells in a 3D environment to different nutrients, growth factors or drug treatments results in ...

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The lab's focus is on developing tools that allow scientists to build upon the intrinsic properties of cells to assemble 3D tissues and synthesize their own extracellular matrix, Morgan explained.

Fibroblasts are found in the connective tissue of our organs, where they ensure that the extracellular matrix is continuously renewed and remains healthy. If an injury occurs or tissue growth is ...

Extracellular matrix (ECM) has previously been recognised as an important element for the growth of various epithelial cells, but rather as a scaffold. A new study shows that ECM can also regulate the ...

Blood is fascinating. Many people learn at school that its function is to transport oxygen and nutrients around the body and remove waste products. But blood has many more functions, including defence ...

More information: Hyeonji Kim et al, Extracellular matrix-based sticky sealants for scar-free corneal tissue reconstruction, Biomaterials (2022). DOI: 10.1016/j.biomaterials.2022.121941 ...

The findings suggest that connective tissue, and extracellular matrix proteins like lumican, operate outside of cells normally, but as disease or damage break down ECM, get sucked into and ...