Power Up! CRISPRi & CRISPRa Tools for Genome-Wide Screening from thescientistllc on Vimeo. Forward genetic screening with CRISPR-Cas9 has created remarkable new opportunities for biological discovery.

Horizon Discovery has announced that it has expanded its functional genomic screening portfolio to include first-to-market CRISPRi (interference) and CRISPRa (activation) screening services. Although ...

In some strains the proteome responses revealed mechanisms that actively buffered the CRISPRi knockdowns. For example, knockdown of homocysteine transmethylase (MetE) in the methionine pathway ...

tuberculosis. Study: Whole genome CRISPRi screening identifies druggable vulnerabilities in an isoniazid resistant strain of Mycobacterium tuberculosis. Image Credit ...