"Genetically engineered plasmid can be used to fight antimicrobial resistance." ScienceDaily. ScienceDaily, 16 September 2019. <www.sciencedaily.com / releases / 2019 / 09 / 190916144006.htm>.

Figure: Image of a bacterial biofilm. Escherichia coli obtained by confocal microscopy. The green bacteria carry an antibiotic resistance plasmid. This plasmid can be transferred to the red bacteria, ...

If the plasmid is lost from the cell, the antidote breaks down, leaving the harmful toxin to attack its host. pCURE plasmids also carry the antidote, ensuring that cells that lose the resistance ...

Birmingham scientists have identified essential genetic code for a method called plasmid curing, which aims to ‘displace’ antibiotic resistance genes from bacteria. Plasmids, which are small, circular ...

The study solves a decades long conundrum in the field, of how the critical protein KorB controls when genes are switched on and off in the multi-drug-resistant plasmid RK2 in bacteria.

More information: Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB, Nature Microbiology (2020).

More information: KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid, Nature Microbiology (2025). DOI: 10.1038/s41564-024-01915-3 ...

Curiosity- driven experiment helps unravel antibiotic-resistance mystery Date: January 23, 2025 Source: John Innes Centre Summary: An international collaboration has achieved an important ...