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Subcellular lipid composition and transport significantly influence the physiological and pathological functions of both ...
Emel Ficici, Wenchang Zhou, Steven Castellano, José D. Faraldo-Gómez, Broadly conserved Na⁺-binding site in the N-lobe of prokaryotic multidrug MATE transporters, Proceedings of the National Academy ...
Nucleotide sugar transporters are integral membrane proteins that play a critical role in eukaryotic glycosylation, the process by which sugars are enzymatically attached to proteins and lipids.
Multidrug and toxic compound extrusion (MATE) transporters mediate excretion of xenobiotics and toxic metabolites, thereby conferring multidrug resistance in bacterial pathogens and cancer cells.
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