Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice ...

Although both ligands activate the classical cAMP and ERK pathways, subtle differences in signal amplitude and kinetics have been observed, thereby enhancing our grasp of receptor-mediated ...

Additionally, while the estrogen signaling pathway was found to be overexpressed, there were no significant changes in estrogen hormone receptors.

Estrogen signaling suppresses tumor-associated tissue eosinophilia to promote breast tumor growth. Science Advances, 2024; 10 (39) DOI: 10.1126/sciadv.adp2442 ...

New generation estrogen receptor-targeted agents in breast cancer: present situation and future prospectives. Acta Materia Medica. 2024. Vol. 3 (1):57-71. DOI: 10.15212/AMM-2024-0006 ...