Technical Terms Enteric Nervous System (ENS): A complex network of neurons and glia located in the gastrointestinal tract that autonomously regulates various aspects of digestive function.

The enteric nervous system (ENS) regulates proper immune response, as well as enzyme and electrolyte secretion, within the jejunum.

The Gut-Brain-Spine Axis and Mental Health The bidirectional communication network between our central nervous system and enteric nervous system (often called our "second brain") occurs through ...

"In particular, emerging evidence indicates that enteric glial cells which are present throughout the gut wall, play central roles in gut homeostasis by supporting enteric nervous system function, ...

Rockefeller University. "How foodborne diseases protect the gut's nervous system." ScienceDaily. ScienceDaily, 30 October 2021. <www.sciencedaily.com / releases / 2021 / 10 / 211030221754.htm>.

Other startups targeting the enteric nervous system include Neurogastrx and Enterin. The growing understanding of glial cells in the gut could inform efforts to develop drugs that target the cells ...

Cavin, J-B., et al. (2023) Intestinal distension orchestrates neuronal activity in the enteric nervous system of adult mice. The Journal of Physiology. doi.org/10.1113/JP284171.