Transcription elongation of the plant RNA polymerase IV is prone to backtracking Journal: Science Advances Published: 2024-08-23 DOI: 10.1126/sciadv.adq3087 Affiliations: 3 Authors: 7 Go to article ...

In order to study its role during the transient elongation process, the researchers needed to isolate a transcription complex at a specific position during RNA synthesis.

Specifically, the team first constructed an HIV-1 transcription model covering both key stages of transcription initiation and elongation (Fig. 1A), where RNA polymerase II (Pol II) interacts with ...

RNA polymerase II (Pol II) generally pauses at certain positions along gene bodies, thereby interrupting the transcription elongation process, which is often coupled with various important biological ...

Both the RNA polymerase II elongation factor ELL3 and RNA polymerase II localize to the nucleus of the mature mouse sperm. This finding raises the possibility that transcription factors could ...

Blocking CTR1 phosphorylation caused the RNA-copying machinery to slow down, resulting in reduced “nascent transcription,” meaning fewer new RNA molecules were being made.

Kai Guo, Xueqiong Du, Lili Tu, Wenxin Tang, Pengcheng Wang, Maojun Wang, Zhen Liu, Xianlong Zhang, Fibre elongation requires normal redox homeostasis modulated by cytosolic ascorbate peroxidase in ...

Dr. Young and lead authors Ozgur Oksuz, Ph.D., and Jonathan E. Henninger, Ph.D., and colleagues discovered that at least half of the approximately 1,600 TFs in the human genome also bind to RNA.