Advanced light microscopy techniques are giving scientists a new understanding of human biology and what goes wrong in ...

Mitochondrial mutations don't seem to build up in women's eggs as they age, which suggests they may have evolved a mechanism ...

"We have obtained a cryo-electron microscopy structure that captures the state of human Rad51 tightly bound to broken DNA," says co-lead author Luay Joudeh, Microscopy Manager at the Departments ...

In our study, we used this technology on human liver organoids to generate a mitochondrial disease model. We employed a clinic-grade technique to repair a mutation in the mitochondrial DNA of ...

Now biologists have discovered that it happens early—in fact, human sperm's few mitochondria contain virtually no DNA at all. The findings were published in a recent issue of Nature Genetics.

Early results are encouraging In the new study, the babies were born to seven women at high risk of transmitting serious, disease-causing mitochondrial DNA mutations to their offspring.

A correction was made on June 17, 2025 : Using information from a photographic agency, a picture caption in an earlier version of this article misstated what kind of electron micrograph was displayed.