A transmission electron micrograph (TEM) showing cardiac muscle cells. Between them is the extracellular space containing collagen, microfibrils, basal laminae and a nerve bundle with eight axons.

Structural knowledge of vertebrate thick filaments in the relaxed state has come from x-ray diffraction and electron microscopy (EM) of striated muscle (4–9).Myosin molecules assemble into bipolar ...

“He was among the first to apply electron microscopy to the study of cardiac tissue. His work directly affected how we understand and treat certain forms of heart disease.” One of Page’s best-known ...

Solutions of human cardiac myosin contain macromolecules which were visualized in the electron microscope by the shadow-casting technic. The dominant particle was observed to be rod-shaped, to have a ...

Confocal and electron microscopy demonstrated characteristic features of native differentiated myocardium; some of these ... contractile force is, in absolute terms, ≈10-fold less than that in ...