We demonstrated that EBF1 functions in distinct regulatory networks: one is composed of EBF1, E2A and Foxo1 and activates the B cell program; the other includes EBF1 and Pax5 and controls the ...

For immune system B cells, researchers have discovered that the transcription factor EBF1 is crucial for B cells to remember who they are. Mature cells develop through a number of immature stages.