Neuroblastoma can be a particularly insidious cancer. In about half of all cases, tumors regress, even without therapy. In ...

Senescent cells are blamed for many effects of aging and as such, they’re targeted by a range of anti-aging therapies. But we might not want to wipe them all out, as a new study suggests that ...

Senescent macrophages have been overlooked for too long. They're not just passive markers of aging—they actively reshape the ...

The quest for rejuvenation treatments often targets senescent cells, despite them having a positive physiological role in health in many recent cases, a leading researcher has warned. In a paper ...

More information: Karl N. Miller et al, p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells, Nature Communications (2025).

T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence ...

This study provides the first comprehensive in vivo characterization of primary and secondary senescent cells at single-cell resolution. By offering unprecedented insights into how senescent cells ...

By Nick Lavars October 13, 2021 A new anti-aging breakthrough could clear out senescent cells with great precision Elymas/Depositphotos View 1 Images ...

While senescent cells typically make up only a small fraction of the overall cell population, they accounted for up to 36 percent of cells in some organs in aging mice, one study showed.

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases. Now scientists have some of the first evidence that at a ...

Proteomic analysis indicates that senescent cells contribute to blood clotting, most likely via stimulation of platelets, suggesting ways to counter chemo-related thrombosis ...