Escherichia coli bacteria imaged by high-speed inline force mapping and fluorescence microscopy. Simultaneous topography and elastic modulus maps show a stiffening of the division site. Light and ...

Light and electron microscopy have distinct limitations. Light microscopy makes it difficult to resolve smaller and smaller features, and electron microscopy resolves small structures, but samples ...

Light microscope images of E. coli cells in transmitted light (left) and reflected light that picks up the red fluorescence of a dye staining the cells' DNA (right). In normal cells (upper panel ...

Light and electron microscopy have distinct limitations ... and Takayuki Uchihashi – chose the common bacteria Escherichia coli to study first in such unprecedented detail.

has been used to characterize the mechanical properties and appearance of dividing E. coli cells at both high resolution and speed. Light and electron microscopy have distinct limitations.