breast cancer resistance protein [BCRP], organic cation transporter [OCT] 2 and multidrug and toxin extrusion protein [MATE] 1). Genotype-dependent drug–drug interactions are also discussed.

Multidrug resistance resulting from the activity of members of the ABC (ATP-binding cassette) family of membrane transporters, which actively pump many types of anticancer drugs out of cancer ...

In chemoradiotherapy resistant OS cells, altered expression of the drug transporter proteins, RFC and ABC family, reduces intracellular drug concentrations. A deeper understanding of osteosarcoma ...

located on the presynaptic membrane can transport NA into presynaptic neurons. In clinical applications, various small molecule drugs inhibit NET to increase the concentration of NA in the ...

His doctoral research was in the area of drug transport in the kidney. His didactic training was broad, with a focus on toxicology. His current research involves investigation of oxalate absorption ...

Derisking of drug-induced liver injury (DILI ... as he discusses how to utilize a two-tiered in vitro assay approach to derisk compounds that inhibit bile-salt transport protein, a known mechanism for ...

The authors' work is supported by the German Cancer Aid (Deutsche Krebshilfe, #107854), the DFG (Deutsche Forschungsgemeinschaft FR1298/5–1) and the DOKTOR ROBERT PFLEGER-STIFTUNG Bamberg ...