More information: Iakovos Lazaridis et al, Striosomes control dopamine via dual pathways paralleling canonical basal ganglia circuits, Current Biology (2024). DOI: 10.1016/j.cub.2024.09.070 ...

Of these four dopaminergic pathways, the nigrostriatal and mesolimbic dopamine systems—which play a key role in reward-seeking behavior, motivation, motor control, and addiction —flow through ...

When we do something that’s reinforcing, that releases dopamine in the reward pathway and tells our brain, “Oh, that’s something you need to do more of. That’s important for survival.” ...

MIT researchers discovered two pathways that arise in the brain’s striatum and connect to dopamine-producing neurons. The pathways appear to relay emotional information that helps to ...

Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior. Cell Reports, 2022; 40 (10): 111309 DOI: 10.1016/j.celrep.2022.111309 ...

In dopamine’s case, that’s actually a lot of neurons; there are multiple different pathways within the brain that use dopamine as a signaling molecule, reflecting the wide range of functions ...

However, given dopamine’s importance to the brain’s reward pathways, its apparent lack of influence on placebo analgesia also raises the question of how those pathways are involved in the ...

There is too much of a good thing. You may be dealing with too much dopamine, making it hard to enjoy simple things. A fast may help, according to a psychiatrist.

The classical go and no-go pathways arise from neurons that surround the striosomes, which are known collectively as the matrix. The matrix cells that give rise to these pathways receive input from ...