New research identifies a promising strategy for correcting dopamine imbalances in the brain using a drug that blocks kappa ...

The present experiments were designed to assess the role of D2-like dopamine receptors in the nucleus accumbens core and shell subregions in cocaine priming-induced reinstatement of drug seeking.

avoidance behavior. These receptors potentially influence anxiety and mood disorders whose origins are still unclear. The team characterized the function of D1 and D2 dopamine receptors in the ...

PHILADELPHIA--(BUSINESS WIRE)--Oncoceutics, Inc. announced that a late-breaking abstract entitled “D2-like dopamine receptor antagonism by ONC201 identified by confluence of computational ...

Some of the antipsychotic medications used in conditions like schizophrenia act as dopamine antagonists. Older, so-called "typical" antipsychotics most commonly act on D2 receptors, while the ...

Medscape: Although it is now established that dopamine D2 receptors are a principal target for antipsychotic drugs, what has been the overall reception to this finding? Now that the D2 target has ...

Those with a higher level of D1 receptors than D2 receptors tended to perform better on memory tasks. fMRI scans showed correspondingly high activation levels in the brain’s prefrontal cortex ...

Researchers found that increased social status and increased social support correlated with the density of dopamine D2/D3 receptors in the striatum, a region of the brain that plays a central role ...

An oral compound, SEP-363856, that does not act on dopamine D2 receptors but has agonist activity at trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT 1A ...

avoidance behavior. These receptors potentially influence anxiety and mood disorders whose origins are still unclear. The team characterized the function of D1 and D2 dopamine receptors in the ...