Distal phototoxic onycholysis and discoloration of the nails are known rare (1:1000) adverse effects of tetracyclines, and this should be explained whenever these substances are prescribed.

Complications of untreated disease include onychomadesis (proximal separation of the nail plate from the nail bed), onycholysis (distal separation of the nail plate from a disruption at the ...

However, onycholysis and shedding of nail plate may ... and a Telfa dressing should be applied prior to bandaging the distal digit firmly. Philip R. Cohen, MD, is a Mohs Micrographic Surgery ...