The passive transfer of IgG offers an alternative way to use the broadly neutralizing HIV-1 antibodies that have recently been identified. The issues related to this strategy of direct antibody ...

Beyond direct neutralization, antibodies induce, through their crystallizable fragment (Fc) domain, innate and adaptive immune responses critical to a successful host immune response against ...

In addition, the boosting of cross-reacting neutralizing antibodies in the SARS-CoV-1–vaccinated serum specimens was further confirmed by direct staining of B cells with the use of virus ...

This remodeling occurred as a direct or allosteric result of the ... to the wild-type RBD and NTD correlated with levels of neutralizing antibodies to these regions, showing their importance ...

Aside from neutralization additional antibody effector functions include both humoral and cell-mediated activity. Complement activation by antibodies leads to direct lysis of the virus and/or ...

These two vaccine candidates show similar drops in neutralizing antibody counts to mRNA-1273 after three months. According to data from Science Direct, antibodies persisted up to six months after ...

Broadly neutralizing antibodies, although arising in some HIV ... "that the known potent HIV bnAbs generally provide poor direct leads to guide HIV vaccine development, because antibodies with ...

The most common way of looking at immunity at the beginning of the pandemic was to check for neutralizing antibodies, which could block the virus's ability to infect new cells. But we've gone ...

we saw the potential of our versatile and rapid platform as something that could be leveraged to deliver benefit to the pandemic by applying an antibody approach to neutralizing the virus. We felt a ...

Jan. 18, 2022 — When we talk about antibodies against COVID-19, we tend to mean the so-called neutralizing antibodies, that offer protection by blocking the virus from invading our cells. Now, a ...

A new, broadly neutralizing antibody developed at Boston Children's Hospital could potentially improve our ability to defend against future variants. In tests, it neutralized all currently known ...