They found that high levels of the gene for dihydrolipoyl transacetylase were associated with lower patient survival. The team also discovered that this DLAT gene was controlled by c-MYC, a protein ...

Pyruvate dehydrogenase kinase 2 (PDHK2) is a unique mitochondrial protein kinase that regulates the activity of the pyruvate dehydrogenase multienzyme complex (PDC). PDHK2 is an integral component of ...

Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p) Andrea Mattevi , Galya Obmolova , Kor H. Kalk , Alex Teplyakov , and Wim G. J. Hol ...