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Researchers have reported finding major differences between postmortem and living prefrontal cortex brain tissues as they relate to one of the most abundant RNA modifications in the brain, known ...
Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes. Nature Communications. doi.org/10.1038/s41467-023-44217-8.
Researchers investigated RNA editing in living and postmortem DLPFC samples, sequencing 206,568 single nuclei from 21 postmortem and 31 living tissues.
Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are perhaps the most important molecules in cell biology, responsible for the storage and reading of genetic information that underpins all life.
A new paper, published today in Science, identifies widespread differences between DNA sequences and their corresponding RNA transcripts in human cells, and demonstrates that these differences result ...