Applied DNA Sciences, Inc. (NASDAQ:APDN) ("Applied DNA" or the "Company"), a leader in PCR-based DNA technologies, today announced that it has acquired Spindle Biotech Inc. ("Spindle"), an early ...

This study reveals that RNA polymerase I uses a unique stalling mechanism at abasic DNA sites, distinct from RNA polymerase II. Pol I’s tendency to stall prevents the production of defective ...

The team tested the Pol 1 inhibitor BOB-42 in animal models, including patient-derived tumors containing the same key genetic markers. The drug reduced tumor growth by up to 77% in melanoma and ...

DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) quantification involves measuring the concentration and assessing the purity of nucleic acids in a given sample. This process is essential as ...

Sugar: In DNA, the sugar is deoxyribose, while in RNA, it is ribose. The sugar forms the backbone of the nucleic acid strand. Phosphate Group: The phosphate group is attached to the sugar and helps ...

PCR, or Polymerase Chain Reaction, is a revolutionary molecular biology technique that allows for the rapid amplification of specific DNA sequences. It is an essential tool in various fields, ...

Scientists provide fresh insights on the origins of life, presenting compelling evidence supporting the 'RNA World' hypothesis. The study unveils an RNA enzyme that can make accurate ...

RNA in control By uncovering RNA’s previously unknown function to repair DNA damage, our findings show how RNA may directly contribute to the stability and evolution of the genome.