DNA replication is a fundamental biological process that enables the accurate duplication of an organism’s genetic material. This intricate mechanism ensures that each new cell receives a complete set ...

During DNA replication, the classic double helix can temporarily rearrange into an alternative structure known as a DNA three ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for ...

In really broad terms, replication stress is when the process of DNA replication — by which DNA is duplicated during the cell cycle — is slowed down or halted due to issues that arise with the ...

Using cultured human cells with genome-edited TEFM knockout, the team studied the effects of deletion of TEFM on mtDNA replication. By knocking out TEFM, they observed a notable reduction in mtDNA ...

The findings visualize for the first time a molecular complex - called CTF18-RFC in humans and Ctf18-RFC in yeast - that loads a "clamp" onto DNA to keep parts of the replication machinery from ...

Mitochondrial single-stranded DNA-binding protein mtSSB is a protein that binds to single-stranded mitochondrial DNA during replication, stabilising it and preventing it from forming secondary ...

New insights into DNA organization during embryonic development Date: September 16, 2024 Source: Hubrecht Institute Summary: Researchers have gained new insights into the mechanism behind the ...