The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a ...

Grant D. Schauer, Michael E. O’Donnell, Quality control mechanisms exclude incorrect polymerases from the eukaryotic replication fork, Proceedings of the National Academy of Sciences of the United ...

Dr. Tsubouchi concludes, "We propose that slow replication forks are not the manifestation of replication impediments but rather an integral feature of DNA replication in ES cells.