This foundation is a short stretch of nucleotides called a primer (Figure 2). After the primer is in place on a single, unwound polynucleotide strand, DNA polymerase wraps itself around that ...
Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...
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POLG diseases: Rare genetic conditions that starve cells of energy and afflicted the late Prince of LuxembourgThese disease-causing mutations are carried by up to 2% of people of Northern European descent ... This gene encodes a protein in mitochondria, called DNA polymerase gamma (pol γ), which is needed to ...
DNA repair proteins act like the body's editors ... understand how cancer cells hijack one of these proteins -- called polymerase theta (Pol-theta) -- for their own survival.
Forensic DNA profiling uses polymerase chain reaction (PCR) to amplify short tandem repeats (STRs), which are highly variable DNA regions, typically with four repeating bases. This variability helps ...
The recombinase disassembles, allowing a DNA polymerase to bind to the 3’ end of the primer, and DNA synthesis begins. “We tested a lot of different polymerases,” said Stemple. “The polymerases that ...
In addition to Lander and Zerio, authors of the study, "Human polymerase θ helicase positions DNA microhomologies for double-strand break repair," include Yonghong Bai, Brian A. Sosa-Alvarado and ...
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