De Duve named these new organelles "lysosomes" to reflect their lytic nature. That same year, Alex Novikoff from the University of Vermont visited de Duve´s laboratory. An experienced ...
Among these, the transcription factors EB (TFEB) and E3 (TFE3) caught Tan’s attention, because their activation coincided with genes that increased lysosome production. TFEB is also an ancient ...
The ER, Golgi apparatus, and lysosomes are all members of a network of membranes, but they are not continuous with one another. Therefore, the membrane lipids and proteins that are synthesized in ...
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Inability of cells to recycle fats can spell disease: Study reveals how a protein helps transport fats out of lysosomesFats and other cellular materials reach the lysosome through three main pathways: endocytosis, phagocytosis, and autophagy. In endocytosis, the cell takes in materials from outside by wrapping ...
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A Novel Function for STING in DNA Damage ResponseCytosolic DNA is a danger signal associated with infections ... of genes responsible for the enhanced biogenesis of lysosomes ...
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