Abstract The molecular mechanisms underlying cytoskeletal alterations in endothelial cells (ECs) during transendothelial migration (TEM) of monocytes are not determined. Tyrosine (Tyr) phosphorylation ...

Adherens junctions (AJs) play an important role in cell-cell mechanical coupling and in maintaining tissue organization. Under chronic flow, epithelial cells adapt by strengthening cell-cell junctions ...

Adherens junctions (AJs) play a fundamental role in tissue integrity; however, the organization and dynamics of the key AJ transmembrane protein, E-cadherin, both inside and outside of AJs, remain ...

Epithelial cells undergo cortical rounding at the onset of mitosis to enable spindle orientation in the plane of the epithelium. In cuboidal epithelia in culture, the adherens junction protein ...

Tight junctions (blue dots) between cells are connected areas of the plasma membrane that stitch cells together. Adherens junctions (red dots) join the actin filaments of neighboring cells ...

Epithelial cells are joined by adherens junctions, which consist of homotypic interactions between extracellular domains of E-cadherins. Inside the cell, the tails of E-cadherins bind actin cables ...

Cell junctions play central roles in regulating cell-cell interactions, tissue architecture and collective cellular behaviors during tissue and organ development and disease progression. As dynamic ...

Background— This review deals with the role of calcium in endothelial cell junctions of the blood-brain barrier (BBB). Calcium is critical for adherens junction function, but it appears that calcium ...

Møllgård et al. studied gap and tight junctions in a sheep model of the ventricular zone germinal matrix. With freeze-fracture electron microscopy they were able to describe not only spirals of ...

Abstract: Adherens junctions (AJs) play an important role in cell-cell mechanical coupling and in maintaining tissue organization. Under chronic flow, epithelial cells adapt by strengthening cell-cell ...