The Crohn’s disease (CD) treatment landscape is undergoing a radical transformation as newer mechanisms of action (MOAs), particularly IL-23 inhibitors and JAK ...

Crohn's disease is a chronic, inflammatory condition that causes abdominal cramps, diarrhea, fever, fatigue, weight loss, and anemia due to the malabsorption of nutrients. There can be other ...

Relevant biomarkers include cytokines and targets such as IL-4, IgE, IL-5, IL-13, IL-33, and TSLP (Figure 2). A number of ...

Guselkumab, a medication with a mechanism of action that is new to inflammatory bowel disease (IBD) treatment, outperformed an established standard of care in promoting intestinal healing and symptom ...

Mirikizumab shows early and sustained efficacy in reducing bowel urgency and achieving remission in patients with moderate-to ...

Crohn’s Disease can lead to complications beyond the gut, such as skin problems, joint pain, and bowel obstruction. There is no single cause, but it is believed to be triggered by a mix of ...

Crohn’s disease and ulcerative colitis, the two main types of IBD, share many of the same symptoms. Per the CDC, common symptoms linked to IBD include diarrhea, stomach pain, fatigue, nausea and ...