New PET radiotracer provides first look at inflammation biomarker in human brain
A novel PET imaging approach can effectively quantify a key enzyme associated with brain inflammation, according to research ...
Nature5y
COX-2 as a multifunctional neuronal modulator
The pro-inflammatory COX-2 enzyme is activated by IL-1β, a blood-borne cytokine that targets the IL-1β type I receptor expressed on endothelial cells (Fig. 1).
WebMD18d
Pain Relief: How NSAIDs Work
NSAIDs are among the most common pain relievers in the world. And lately, they're among the most controversial. Find out what these anti-inflammatory pills actually do inside your body. NSAIDs ...
Medscape7d
Defining the COX Inhibitor Selectivity of NSAIDs: Implications for Understanding Toxicity
BAE: Bovine aortic endothelial; RHP: Recombinant human protein. NSAIDs variably inhibit prostaglandin H synthase (COX). COX-2 was cloned in 1991, and it was subsequently established that COX-1 ...
EurekAlert!2d
New PET radiotracer provides first look at inflammation biomarker in the human brain
A novel PET imaging approach can effectively quantify a key enzyme associated with brain inflammation, according to research ...
Medscape25d
Defining the COX Inhibitor Selectivity of NSAIDs: Implications for Understanding Toxicity
From the crude animal tissue preparations initially used in vitro (e.g., homogenate of guinea pig lung), more sophisticated assay systems have been developed for determining NSAID inhibition of ...