These new bonds were only discovered in 2016, and are formed when the end of a lysine side-chain is linked to the end of a cysteine side-chain with an oxygen atom linking them together.

Covalent bonds, in which two atoms are bound together by sharing a pair of electrons, form the scaffolding that underpins the majority of organic compounds. In 1931, the Nobel Laureate Linus ...

Template-assisted synthesis dramatically improves the yield of functionalized oligophenylene cages, report researchers from ...

In 1931, the Nobel Laureate Linus Pauling suggested that covalent bonds made from just a single, unpaired electron could exist, but these single-electron bonds would likely be much weaker than a ...

Covalent chemical probes – chemical probes that form a covalent bond with their target biomacromolecule(s) represent powerful tools that can be used for biology discovery, target validation (or ...

Katherine Bourzac is a freelance journalist in San Francisco, California. For a little more than a century, chemists have known that strong atomic links called covalent bonds are formed when atoms ...

It described an unnatural amino acid that can turn a protein into a covalent binder (Cell 2020, DOI: 10.1016/j.cell.2020.05.028). “It was pretty clear to us both very early that this was a ...

Prior to 2000, many drugs that formed a covalent bond with targets did so non-selectively, which often led to undesired side effects when compared to non-covalent drugs. This led to the belief that ...

Solvay, a global market leader in specialty materials, has expanded its range of FusePly ® chemical bonding technology with a second product, FusePly ® 250, designed to bond composite structures at ...