Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467 ...

Reference: Zeng Z, Huang B, Parvez RK, et al. Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors. Nat Commun.

Vinculin is a 117–130 kDa cytoskeletal protein containing 1066 amino acids (1, 2, 3). Its gene is encoded on human chromosome 10q11.2-qter (4). Recently, the complete sequences of human as well ...

An additional molecular cocktail pushed ureteric bud organoids -- grown from either mouse UPCs or human stem cells -- to reliably develop into even more mature and complex collecting duct ...

In a new study in Nature Communications, Zhongwei Li and his colleagues describe how they can generate rudimentary kidney structures, known as organoids, that resemble the collecting duct system ...