Huntingtin was the first disease gene mapped to a specific chromosome. How did scientists do it and what have we learned since then? HD is a rare, adult-onset, autosomal dominant, progressive ...

In particular, it explains that humans have one fewer chromosome pair in their cells than apes, due to a mutation found in chromosome number 2 that caused two chromosomes to fuse into one.

Human biological sex is determined by the sex chromosomes X and Y. In most cases, females possess two X chromosomes, while males have one X and one Y. However, there is some evidence that the Y ...

The nucleus of each human body cell contains 46 chromosomes. Each chromosome contains about 1000 genes. There is enough DNA in all the cells in a human body to stretch to the sun and back again ...

The centromeres of human chromosomes are heterochromatic regions ... as platelike structures composed of several layers (Figure 4). In addition, multiple microtubules appear to insert into the ...