Japanese scientists may have rewritten the future of Down syndrome research by using gene editing to remove the extra ...

Down syndrome, which causes a range of developmental differences and affects 1 in 700 newborns in the United States, is caused by the presence of an extra copy of chromosome 21. Mongkolchon ...

Occurring in about one per eight hundred births, Down syndrome - or trisomy 21 - is the most frequent genetic cause of intellectual disability. It results from a chromosomal abnormality where cells of ...

Japanese researchers, led by Ryotaro Hashizume at Mie University, have used CRISPR-Cas9, a gene-editing tool, to remove the extra chromosome 21 from lab-grown cells.

The chromosome 10 mice, which had memory problems, were found to have distinct abnormalities in the brain’s hippocampus, which is critical for memory. The chromosome 16 mice also had some ...

Down syndrome, or trisomy 21, is caused by the presence of a third copy of the 21st chromosome. Affected individuals have inherited two copies of chromosome 21 from one parent and one copy from ...

Testing for trisomy 21 is shown as an illustrative example. In random sequencing, cell-free DNA (cfDNA) fragments originating from any chromosome are sequenced. A random representative selection ...

The evolution of de novo human‐specific microRNA genes on chromosome 21. American Journal of Biological Anthropology, 2022; DOI: 10.1002/ajpa.24504 ...